IGlycine iyi-amino acid esetshenziswa ngumzimba ukwakha amaprotheni. Le nhlanganisela futhi isebenza njengesisekelo sokwakheka kwama-molecule we-creatine, porphyrin, serotonin, ne-purine nucleotide kumaseli.
Amalungiselelo ngale-amino acid asetshenziswa kwezokwelapha njengezikhuthazi ze-neurometabolic. Kwezokudla kwezemidlalo kusetshenziswa kaningi njengesithasiselo sokudla esiguqula ukunambitheka nephunga lomkhiqizo, kwesinye isikhathi njengengxenye yokuthambisa.
Umphumela emzimbeni
I-Glycine iyi-acid ye-neurotransmitter. Ebuchosheni nasentanjeni yomgogodla, ama-glycine sensory neurons yizona ezithola izivimbelo eziningi kakhulu.
Ngokuzijoyina, le-amino acid inciphisa ukukhishwa kwezinto ezijabulisayo ezivela kumaseli ezinzwa futhi yandisa ukukhishwa kwe-gamma-aminobutyric acid, i-neurotransmitter ebaluleke kakhulu yohlelo lwezinzwa oluphakathi. I-Glycine ibuye ibe nomthelela wokuvimbela ama-neurons entanjeni yomgogodla, enesibopho sokugcina ithoni yemisipha nokuhlangana kwezimoto.
IGlycine inemiphumela elandelayo:
- ukunciphisa ukucindezeleka ngokomzwelo;
- ukunciphisa ulaka;
- ukwenza ngcono ikhono lokuzivumelanisa nomphakathi;
- ukwanda kwethoni yemizwa;
- ukwenza lula ukulala, ukujwayela ukulala;
- ukunciphisa imiphumela emibi yokuvezwa kwezinto ezinobuthi ezicutshini zobuchopho (kufaka phakathi i-ethanol, izinhlanganisela ezinobuthi zemithi);
- Ukubuyiselwa kwesakhiwo nokusebenza kwamaseli obuchopho ngemuva kokuhlukumezeka, ukuvuvukala, kanye ne-ischemia.
Ama-molecule we-Glycine mancane, ngakho-ke angena ngokukhululekile kwizicubu nangoketshezi lomzimba, anqobe isithiyo segazi nobuchopho. Emangqamuzaneni, le nhlanganisela iyawohloka ibe amanzi ne-carbon dioxide, aqedwa kalula, ngakho-ke, i-glycine ayiqoqeki ezicutshini.
Isicelo kwezokwelapha
I-Glycine isetshenziswa kakhulu ekwenziweni kwemizwa njengesidakamizwa se-nootropic ne-anti-anxiety, i-antidepressant emnene. Kunqunywe ezigulini ezithatha ama-antipsychotic asindayo, ama-antipsychotic, ama-hypnotics anamandla, ama-anticonvulsants ukunciphisa ukushuba kwemiphumela emibi.
Futhi, i-amino acid isetshenziswa ngamanye ama-narcologists ekwelapheni izimpawu zokuhoxa ezikhula ngemuva kwesizinda sokuhoxiswa kotshwala, ama-opiates nezinye izinto ezithinta ingqondo, njenge-sedative, tranquilizer. Kwesinye isikhathi kunqunyelwe ukuthuthukisa inkumbulo nokusebenza kwengqondo, izinqubo zokuhlangana.
Isixazululo esingu-1.5% se-glycine sisetshenziswa ngesikhathi sokuhlinzwa kwe-transurethral ekusebenzeni kwe-urological ukufutha i-urethra.
Izinkomba zokusetshenziswa
Izinkomba zokuthatha izidakamizwa nge-amino acid:
- ukwehla kokusebenza kwengqondo;
- ukuba sesimweni sokucindezeleka, ukucindezeleka okukhulu ngokomzwelo isikhathi eside;
- ukuphambuka komphakathi kwezingane nentsha;
- ukushaywa yischemic;
- i-vegetative vascular dystonia;
- ama-neuroses kanye ne-neurosis-like states;
- izinhlobo ezahlukahlukene ze-encephalopathy (kufaka phakathi lezo ezikhula esikhathini sokubeletha);
- I-pathologies yesistimu yezinzwa ephakathi, ebonakala ngokuphazamiseka kwesizinda se-psychoemotional, ukuphazamiseka kokulala, ukukhathazeka ngokweqile, ukuwohloka kwamakhono okuqonda.
I-Glycine inconywa ukuthi ithathwe ukunciphisa imiphumela yokulimala okulimazayo kobuchopho, izifo ezithathelwanayo zobuchopho.
Isichasiselo sithi lesi sidakamizwa asinakho ukuphikisana. Ngaphandle kwezimo zokungabekezelelani ngakunye kwalolu ketshezi. I-amino acid inqunyelwe ngisho nabesifazane abakhulelwe nabancelisayo, kepha ikhambi lingathathwa kuphela ngemuva kokubonisana nodokotela.
Izinzuzo ze-glycine zabasubathi
IGlycine ibalulekile kubasubathi, njengawo wonke amanye ama-amino acid, lapho umzimba wakha khona ama-molecule wamaprotheni.
Kubalulekile ukuyisebenzisa ngokudla, futhi ukudla okwengeziwe kunconywa kuphela ngezikhathi zokukhuphuka kwengcindezi, ikakhulukazi ngokwengqondo nangokomzwelo. Kubasubathi, lesi yisikhathi sokuncintisana, lapho kungadingeki kuphela imininingwane emihle yomzimba, kepha futhi nekhono lokuhlola isimo, gxila ekufezeni inhloso. Ukuzola, ukukhuthazela, ukusebenza kwengqondo okuphezulu kuyadingeka kwezemidlalo okungekho ngaphansi kwamandla amahle kakhulu, isivinini nezinye izinkomba.
Imvamisa, abagijimi bathatha i-glycine ngezifundo zamaviki ama-2-4 ngesikhathi sokuqeqeshwa ngaphambi komncintiswano kanye nomncintiswano uqobo. Ithuthukisa imizwa, inyuse ugqozi, futhi inciphise amazinga okucindezeleka.
I-amino acid ikuvumela ukuthi uqoqe ngangokunokwenzeka, ikhuthaza ukululama okusheshayo ngaphansi kokucindezeleka okukhulu.
Ukushoda kweGlycine
Ukuntuleka kwe-glycine emzimbeni kubonakala ngezimpawu ezilandelayo:
- kwehle isimo sokuzivikela komzimba;
- ukunciphisa ijubane lamaprotheni metabolism;
- ingozi eyengeziwe yokulimala;
- ukuwohloka kwesimo sezinwele, izipikili, isikhumba;
- ukuphazamiseka kohlelo lokugaya ukudla.
Ukuntuleka kwale-amino acid emzimbeni kubonakala ekukhiqizeni i-hormone yokukhula.
Imithombo yokudla ye-glycine
Njengamanye ama-amino acid, abantu bathola i-glycine ekudleni. Imithombo yayo eyinhloko yile:
- imidumba (ubhontshisi, amakinati);
- inyama yenkomo;
- isikhukhukazi;
- inyama yokudla, ikakhulukazi isibindi senyama yenkomo nenkukhu;
- amantongomane;
- i-cottage shizi;
- imbewu yamathanga;
- inkukhu, amaqanda ezigwaca;
- okusanhlamvu, ikakhulukazi i-buckwheat, i-oatmeal.
Amanani wokusebenzisa
Esikhathini sokucindezeleka okukhulu ngokomzwelo, i-glycine inconywa ukuthi ithathwe izikhathi ezingu-2-3 ngosuku, ithebhulethi eli-1 (100 mg yezinto ezihlanzekile). Umkhiqizo uthathwa ngokuncanyana (ngaphansi kolimi), ngaphandle kokudla.
Ngokuphazamiseka kokulala, izinkinga zokulala ngenxa yokucindezeleka ngokomzwelo, i-glycine ithathwa ebusuku, imizuzu engama-20-30 ngaphambi kokulala, ithebhulethi elilodwa.
Okuqhamuka uma udla imishanguzo
Kwezinye izimo, lapho uthatha i-amino acid, isikhumba ukusabela komzimba ukuthuthukisa ngesimo ukuqubuka kwesikhumba, ukulunywa, i-urticaria.
Ukweqiwa ngokweqile kweGlycine akuzange kubhalwe. Lokhu kungenxa yokuthi le nhlanganisela ngokwemvelo ikhona ezicutshini, futhi umzimba uzohlala uthola ukusetshenziswa kwe-amino acid.
Uma kuvela imiphumela emibi lapho uthatha lo muthi, yeka ukusetshenziswa bese uthintana nodokotela ukuthola izeluleko.
I-Glycine iwumuthi ongawutholi futhi ungathengwa ngokukhululeka kunoma iyiphi ikhemisi. Izindleko zokupakisha umuthi oshibhile wamathebulethi angama-50 cishe zingama-ruble angama-40, kuya ngomkhiqizi, amanani ahluka kakhulu.
Ucwaningo
Ngokokuqala ngqa, i-glycine yahlukaniswa futhi yachazwa usokhemisi nomsokhemisi waseFrance uHenri Braconneau. Usosayensi wathola amakristalu amnandi ngesikhathi sokuhlolwa kwe-gelatin ngawo-20s wekhulu le-19. Futhi kuphela ngo-1987 lapho kuchazwa khona izakhiwo ze-cytoprotective zale-amino acid. Kutholakale ukuthi kukhuthaza ukubuyiselwa kwamaseli aphilayo ngemuva kwe-hypoxia. Ukuhlolwa kwezilwane kukhombisile ukuthi le nhlanganisela isetshenziswa ngumzimba ukunciphisa imiphumela ye-ischemia - ukwephula ukunikezwa kwegazi.
Kodwa-ke, ngaphansi kwezimo zokuxineka okukhulu, ngokwesibonelo, ngesifo sohlangothi, i-glycine okwesikhashana iba i-amino acid enesimo esithile, okungukuthi, ayinakuhlanganiswa ngumzimba.
Lapho yethulwa ngaphandle, ivikela ngokuphelele amaseli endlaleni yomoya-mpilo. Mhlawumbe, i-glycine inciphisa ukutholakala kolwelwesi lweseli, ngaleyo ndlela kugcinwe ibhalansi ye-electrolyte futhi kuvimbele ukonakala kwesakhiwo seseli.
Ngokuyinhloko, ososayensi baseRussia benza izifundo ze-amino acid, eNtshonalanga yaziwa njengengasebenzi futhi cishe ayifundwanga. Ukusetshenziswa kwendawo kuphela e-United States kuyisixazululo sokunisela ukungenelela kwe-transurethral.
Ososayensi baseRussia bamatasa kakhulu bacwaninga nge-nootropic, tranquilizing, antitoxic, anti-depressant properties ye-glycine. Abanye babo bakhombisile umphumela wale nhlanganisela ekuqedeni ukuphazamiseka kokulala.
I-glycine nomphumela we-neuroprotective okhonjisiwe: uma uthathwe emahoreni okuqala ama-3-6 ngemuva kokushaywa yischemic, umuthi unciphisa ubukhulu bemiphumela yawo. Futhi, ososayensi baseRussia bafinyelela esiphethweni sokuthi ukusetshenziswa kwe-amino acid kunethonya lokuthambisa njenge-nootropic.
Ozakwethu baseNtshonalanga abahambisani nombono wabaphenyi baseRussia, bekholelwa ukuthi zonke izenzo ezibonwayo zibangelwa umphumela we-placebo. Ngempela, akukaze kwenzeke ukufakazela ukusebenza komuthi usebenzisa umuthi osuselwa ebufakazini.
Umphumela
Singasho ukuthi i-glycine inomphumela omuhle, kepha inqubo yayo ayikasungulwa. Kungaba yi-placebo, kepha kuyasebenza impela. Kunoma ikuphi, ngeke kube nemiphumela emibi ekuthatheni lesi sidakamizwa, noma kumithamo ephezulu, eyenza ukuthi odokotela bakwazi ukuyinikeza ngaphandle kokwesaba ezigulini ezahlukahlukene.
