I-Acetylcarnitine (i-Acetyl-L-carnitine noma i-ALCAR ngamafuphi) iyifomu le-ester le-amino acid L-carnitine okuxhunywe kuyo iqembu le-acetyl. Abenzi bezithasiselo zemidlalo eziqukethe i-ALCAR bathi le fomu ye-L-carnitine isebenza kangcono ekusetshenzisweni kwezemidlalo, njengoba inokutholakala okuphezulu, ngakho-ke ingasetshenziswa kumithamo encishisiwe enomphumela ofanayo. Kodwa-ke, kufanele kukhunjulwe ukuthi le mpikiswano ayikaqinisekiswa.
Izici zefomu le-acetyl, umehluko phakathi kwe-L-carnitine ne-acetylcarnitine
I-Acetylcarnitine ne-L-carnitine yizinhlobo ezimbili ezihlukene zenhlanganisela efanayo enezakhi zamakhemikhali ezifanayo, kodwa zinezici ezihlukile.
L-carnitine
I-L-carnitine (i-levocarnitine) iyi-amino acid, ikhompiyutha ehlobene namavithamini e-B, futhi ingesinye sezixhumanisi eziyinhloko ekuguqulweni kwamafutha kumaseli. Le nto ingena emzimbeni womuntu nokudla (inyama, ubisi nemikhiqizo yobisi, izinkukhu), futhi iphinde ihlanganiswe esibindini nasezinso, lapho isatshalaliswa khona kwezinye izicubu nezitho.
Ezinye izinqubo ezibalulekile zamakhemikhali emzimbeni azikwazi ukuqhubeka kahle ngaphandle kwe-L-carnitine. Ukuntuleka kwalesi sakhi kungabangelwa ukuthambekela kwefa noma izimo zokugula, ngokwesibonelo, isifo sezinso esingalapheki. Futhi, ukwehla kokuhlanganiswa kwe-L-carnitine kungabangela ukuphuza imithi ethile, isibonelo, i-meldonium.
Ngokushoda kwe-carnitine emzimbeni, odokotela bancoma izidakamizwa ezibuyisa futhi zigcine okuqukethwe kwezicubu. Ngezinhloso zokwelapha, i-L-carnitine isetshenziselwa ukwelapha izifo zenhliziyo nemithambo yegazi, ezinye izinhlobo ze-dystrophy yemisipha eqhubekayo, i-thyrotoxicosis, ukubambezeleka kokukhula ezinganeni, isikhumba nezinye izifo eziningi.
I-L-carnitine nayo ithathwa ngabantu ababambe iqhaza kwezemidlalo. Izithako zokudla okunempilo zezemidlalo eziqukethe ama-amino acid zisetshenziswa njenge-accelerator yezinqubo ze-metabolic.
Ngokuzivocavoca umzimba okukhulu, i-L-carnitine isiza ukuguqula ama-fatty acids abe amandla, ngakho-ke kunconywa ukuwathatha ukusheshisa ukulahleka kwesisindo nokushisa amafutha. Ukukhishwa okukhulu kwamandla kusiza ukukhulisa ukusebenza kahle koqeqesho ngokwandisa ukukhuthazela.
Phambilini bekucatshangwa ukuthi i-L-carnitine ivula imisebenzi ye-anabolic, kepha leli phuzu lokubuka liphikisiwe. Noma kunjalo, izithasiselo ezinalolu hlobo ziyaqhubeka zithandwa kwezemidlalo. Uma ihlanganiswa kanye ne-steroids, imiphumela ye-L-carnitine iyathuthukiswa.
I-Acetylcarnitine
I-Acetylcarnitine ifomu le-ester le-L-carnitine lapho iqembu le-acetyl linamathiselwe khona. Ngokungafani nezinye izinhlobo zale-amino acid, ingawela isihlungi sobuchopho esivikelayo esibizwa ngokuthi yisithiyo segazi nobuchopho.
Abakhiqizi be-Supplement bavame ukuthi i-acetylcarnitine iyindlela entsha futhi “ethuthukile” ye-L-carnitine, isengezo semidlalo esimi isikhathi eside, ngaleyo ndlela ikhuthaza abantu ukuthi bathenge imikhiqizo yabo. Kodwa-ke, empeleni, uma usebenzisa imithamo efanayo yento, ukugxila kwefomu le-acetyl egazini kuphansi, okungukuthi, ukutholakala kwayo kuphansi kunalokho kwefomu elula levocarnitine. Ngakho-ke, ungazethembi izethembiso zabakhangisi.
Uma umgomo womuntu ukwehlisa isisindo, yenza amafutha omzimba ajwayelekile emzimbeni, khona-ke kungcono ukwengeza nge-L-carnitine ngendlela ejwayelekile noma nge-tartrate. Kepha ikhono lefomu le-acetyl lokunqoba isithiyo segazi nobuchopho lisetshenziswa kakhulu kwezokwelapha kuzo zombili izinhloso zokwelapha kanye neprophylactic.
I-Acetylcarnitine ingena ngaphakathi kwezicubu zesistimu yezinzwa emaphakathi, ngaleyo ndlela inyuse izinga eliphelele le-carnitine ebuchosheni. Izakhiwo ezinjalo ze-acetylcarnitine zenza kube nokwenzeka ukusebenzisa izidakamizwa ezisekelwe kukho ekwelapheni izifo nemibandela elandelayo:
- Isifo i-Alzheimer;
- ukuwohloka komqondo kwe-cerebrovascular;
- i-peripheral neuropathies, noma ngabe ivela kuphi;
- i-encephalopathy yemithambo kanye nama-syndromes wokuzibandakanya akhula ngemuva kwabo;
- ukuwohloka kwemisebenzi yokuqonda kwengqondo, kufaka phakathi izinguquko ezihlobene nobudala, kanye nokwehla kokusebenza kobuchopho ngokumelene nesizinda sokudakwa isikhathi eside (isibonelo, utshwala);
- ukukhathala okuphezulu kwengqondo;
- ukukhubazeka kwengqondo ezinganeni.
I-Acetylcarnitine isetshenziswa njenge-neuroprotector, isidakamizwa se-neurotrophic, esinomphumela we-cholinomimetic, ngoba isakhiwo sayo sifana ne-neurotransmitter acetylcholine.
Kunconywa ukuba uthuthukise ukusakazwa kobuchopho, uthuthukise ukuvuselelwa kwemicu yezinzwa.
Imodi yesicelo
Abakhiqizi abahlukahlukene bancoma imithamo ehlukene nemizila yokuphatha. Imvamisa, izithasiselo zemidlalo ezine-acetylcarnitine ziyelulekwa ukuthi zithathwe ngaphambi noma ngesikhathi sokudla, kanye namahora angu-1-2 ngaphambi kokuqeqeshwa. Imithi esuselwa kule nhlanganisela iphuzile ngaphandle kokudla.
Isidingo sansuku zonke se-carnitine asikasungulwa njengoba singesona isakhi somzimba esibalulekile.
Umthamo omuhle uthathwa njenge-500-1,000 mg ye-acetylcarnitine emsulwa ngomthamo ngamunye. Itholakala kuwo womabili amaphilisi kanye nempuphu yokwakha kabusha ngamanzi.
Uma usebenzisa izidakamizwa nezithako nge-acetylcarnitine, imiphumela emibi cishe ayibonwa. Ngezikhathi ezithile, isicanucanu, isilungulela, ukuphazamiseka kokugaya ukudla, kungenzeka ikhanda elibuhlungu, kepha, njengokujwayelekile, ukusabela okunjalo kuhlotshaniswa nokusetshenziswa okungalungile kwezimali, izinguquko ezingafanele emithamo.
Izimo zokwamukela ukukhulelwa ukukhulelwa, ukuncelisa ibele, ukungabekezelelani ngakunye.
Qiniseka ukuthi uthintana nodokotela ngaphambi kokusebenzisa izidakamizwa ezine-acetylcarnitine kubantu abaphethwe yizifo ezilandelayo:
- i-renal, ukwehluleka kwesibindi;
- isithuthwane;
- izifo zenhliziyo, imithambo yegazi;
- ukwephulwa kwezinga lomfutho wegazi (kokubili ukwanda nokuncipha);
- ukuqina kwesibindi;
- isifo sikashukela;
- ukuphazamiseka kokulala;
- ukuphazamiseka komsebenzi wokuphefumula.
I-Acetylcarnitine ifakwa i-hydrolyzed egazini, engakhombisa ukusebenza kwayo okuphansi kwebhayoloji. Inzuzo yale nto kwezemidlalo ngezinhlobo ezijwayelekile ze-L-carnitine iyangabazeka, futhi izindleko zezithasiselo ngayo ziphakeme kakhulu.
Mhlawumbe akunangqondo ukuthenga izengezo ezibiza kakhulu zokudla nge-acetylcarnitine. Ngakolunye uhlangothi, le nto futhi ithuthukisa ukukhiqizwa kwamandla ngesikhathi sokuzivocavoca, ngenkathi futhi iba nomthelela omuhle ekusebenzeni kobuchopho.
