Ama-amino acid ayizinhlanganisela eziphilayo ezakha amaprotheni. Phakathi kwazo kunezinto ezingashintshwa ezithatha umzimba wethu ezikwazi ukuzihlanganisa, nezinye ezingenakubuyiselwa emuva eza nokudla kuphela. Okubalulekile (okubalulekile) kufaka ama-amino acid ayisishiyagalombili, kufaka phakathi i-isoleucine - L-isoleucine.
Cabanga ngezici ze-isoleucine, izakhiwo zayo zemithi, izinkomba zokusetshenziswa.
Izici zamakhemikhali
Ifomula yokwakheka kwe-isoleucine ithi HO2CCH (NH2) CH (CH3) CH2CH3. Le nto inezici ezinomsoco omncane.
I-amino acid isoleucine iyingxenye yamaprotheni amaningi. Idlala indima ebalulekile ekwakheni amaseli omzimba. Njengoba inhlanganisela ingahlanganisiwe yodwa, kufanele inikezwe inani elanele ngokudla. Isoleucine iyi-branched chain amino acid.
Ngokushoda kwezinye izingxenye ezimbili zokwakheka kwamaprotheni - i-valine ne-leucine, i-compound iyakwazi ukuguqula ibe yizo ngesikhathi sokuphendula kwamakhemikhali okuthile.
Indima yebhayoloji emzimbeni idlalwe uhlobo lwe-L lwe-isoleucine.
Umphumela wemithi
I-amino acid ingeyama-anabolic agents.
I-Pharmacodynamics ne-pharmacokinetics
Isoleucine ibandakanyekile ekwakheni amaprotheni emisipha yefibre. Lapho uthatha umuthi oqukethe i-amino acid, isithako esisebenzayo sidlula isibindi bese sithunyelwa emisipheni, esheshisa ukutakula kwayo ngemuva kwe-microtraumatization. Le mpahla yokuxhuma isetshenziswa kakhulu kwezemidlalo.
Ekubunjweni kwama-enzyme, le nto inyusa i-erythropoiesis emnkantsheni wethambo - ukwakheka kwamangqamuzana abomvu egazi, futhi ngokungaqondile ibambe iqhaza ekusebenzeni kwezicubu zomzimba. I-amino acid isebenza njenge-substrate yokuphendula ngamandla kwe-biochemical, ithuthukisa ukusetshenziswa kwe-glucose.
Le nto iyisici esibalulekile se-microflora yamathumbu, inomphumela wamagciwane ngokumelene namanye amabhaktheriya e-pathogenic.
I-metabolism eyinhloko ye-isoleucine yenzeka ezicutshini zemisipha, kuyilapho i-decarboxylated iphinde ikhishwe emchameni.
Izinkomba
Izidakamizwa ezisekelwe e-Isoleucine zinqunyelwe:
- njengengxenye yokudla kwabazali;
- ne-asthenia ngokumelene nezifo ezingapheli noma indlala;
- ukuvimbela isifo sikaParkinson nezinye izifo zemizwa;
- nge-dystrophy yemisipha yemvelaphi ehlukahlukene;
- esikhathini sokuvuselelwa ngemuva kokulimala noma ukuhlinzwa;
- ezifweni ezibucayi nezihlala njalo zokuvuvukala kwamathumbu;
- Njengengxenye yokwelashwa okuyinkimbinkimbi nokuvimbela izifo zegazi kanye nesistimu yenhliziyo.
Izimo
Ukungafani kokuthatha isoleucine:
- Ukuphazanyiswa kokusetshenziswa kwe-amino acid. I-pathology ingabangelwa ezinye izifo zofuzo ezihambisana nokungabikho noma umsebenzi owanele wama-enzyme abandakanyeka ekuwohlokeni kwe-isoleucine. Kulokhu, ukuqoqwa kwama-organic acid kwenzeka, futhi i-acidemia iyakhula.
- I-Acidosis, eyavela ngemuva kwezifo ezahlukahlukene.
- Isifo esingapheliyo sezinso esinokwehla okuphakeme kumthamo wokuhlunga wezinto ezisetshenziswayo ezibengezelayo.
Okuqhamuka uma udla imishanguzo
Imiphumela emibi ngenkathi uthatha i-isoleucine ayivamile. Amacala wokukhula kokungezwani komzimba, ukungabekezelelani kwe-amino acid, isicanucanu, ukuhlanza, ukuphazamiseka kokulala, ikhanda elibuhlungu, ukwanda kokushisa komzimba kumanani amancane. Ukubonakala kokungathandeki ezimweni eziningi kuhlotshaniswa nomthamo owedlulele wokwelashwa.
Imiyalo yokusetshenziswa
I-L-isoleucine itholakala ezidakamizweni eziningi. Indlela yokuphatha, isikhathi sesifundo kanye nomthamo kuncike kwifomu lomuthi kanye nezincomo zikadokotela oya khona.
Izithako zemidlalo ezine-isoleucine zithathwa ngesilinganiso esingu-50-70 mg nge-1 kg yesisindo somzimba.
Ngaphambi kokusebenzisa isengezo sokudla, kufanele ufunde imiyalo, ngoba umthamo ungahluka. Isikhathi sokuthatha isengezo sincike kuzimpawu zomzimba ngamunye.
Ukweqisa ngokweqile
Ukwedlula umthamo omkhulu ovunyelwe kuholela ekuguleni okuvamile, isicanucanu, nokuhlanza. I-Organic acidemia iyakhula. Lokhu kuveza iphunga elithile lomjuluko nomchamo, okusikhumbuza isiraphu ye-maple. Ezimweni ezimbi kakhulu, ukuvela kwezimpawu zemizwa, ukudlikizela, ukucindezeleka kokuphefumula, kanye nokwanda kokuhluleka kwezinso kungenzeka.
Ukungezwani komzimba ngendlela ye-eczema, i-dermatitis, i-conjunctivitis kungenzeka.
Ukwelashwa ngokweqile kuhlose ukukhulula izimpawu nokususa i-isoleucine eyeqile emzimbeni.
Ukusebenzisana
Akukho ukuxhumana kwe-isoleucine nezinye izidakamizwa okutholakele. Isakhi siwela isithiyo segazi nobuchopho futhi singavimbela i-tryptophan ne-tyrosine kancane.
Ukufaniswa okuphezulu kuphawulwa ngokudla ngasikhathi sinye kwenhlanganisela enamafutha emifino nezilwane.
Imigomo yokuthengisa
Imithi ye-amino acid iyatholakala ngaphandle kwemithi kadokotela.
Imiyalelo ekhethekile
Lapho kukhona izifo ezibolile zezinhliziyo, izinhlelo zokuphefumula kanye nesifo esingapheliyo sezinso, kungenzeka ukunciphisa umthamo wokwelashwa ube ubuncane.
Akunconywa ukuhlanganisa ukwamukelwa ne-folic acid, ngoba i-compound inciphisa ukuhlushwa kwayo.
Le ngxube inikezwe ngokucophelela ezigulini ezine-arrhythmias yenhliziyo, ngoba i-amino acid inciphisa ukugxila kwe-sodium ne-potassium egazini.
Ngesikhathi sokukhulelwa kanye ne-lactation
Imithi ingeyeqembu le-FDA A, okungukuthi, ayisiyona ingozi enganeni.
Isoleucine ngokweqile nokushoda
Ukweqisa kwe-isoleucine kuholela ekwakhiweni kwe-acidosis (ushintsho olubucayi ebhalansi lomzimba lubheke ku-asidi) ngenxa yokuqoqwa kwama-organic acid. Ngesikhathi esifanayo, izimpawu zokugula ngokweqile, ukozela, isicanucanu ziyavela, nokwehla kwemizwelo.
I-acidosis enamandla ibonakala ngokuhlanza, ukukhuphuka kwengcindezi yegazi, ubuthakathaka bemisipha, ukuzwela okungakhubazekile, ukuphazamiseka kwe-dyspeptic, ukukhuphuka kwenhliziyo nokunyakaza kokuphefumula. Ama-pathologies ahambisana nokwanda kokuhlushwa kwe-isoleucine namanye ama-amino acid ane-branched-chain ane-ICD-10 code E71.1.
Ukushoda kwe-Isoleucine kuvela ngokudla okuqinile, ukuzila ukudla, izifo ezingamahlalakhona zomgudu wamathumbu, uhlelo lwe-hematopoietic nezinye izifo. Ngesikhathi esifanayo, ukwehla kwesifiso sokudla, ukunganaki, isiyezi, ukuqwasha.
Isoleucine ekudleni
Inani elikhulu kakhulu lama-amino acid litholakala ekudleni okunothe ngamaprotheni - izinkukhu, inyama yenkomo, ingulube, unogwaja, inhlanzi yasolwandle, isibindi. Isoleucine itholakala kuyo yonke imikhiqizo yobisi - ubisi, ushizi, i-cottage shizi, ukhilimu omuncu, i-kefir. Ngaphezu kwalokho, ukudla kwezitshalo nakho kunenhlanganisela ezuzisayo. I-amino acid icebile kubhontshisi, i-watercress, i-buckwheat, udali, iklabishi, i-hummus, ilayisi, ummbila, imifino, izimpahla ezibhakiwe, amantongomane.
Itafula likhombisa isidingo sansuku zonke se-amino acid kuye ngempilo.
| Inani lama-amino acid kumagremu | Indlela Yokuphila |
| 1,5-2 | Akusebenzi |
| 3-4 | Maphakathi |
| 4-6 | Kuyasebenza |
Amalungiselelo aqukethe
I-compound iyingxenye ye:
- imithi yokwondliwa kwabazali nabangaphakathi - Aminosteril, Aminoplasmal, Aminoven, Likvamin, Infezol, Nutriflex;
- amavithamini izakhiwo - i-Moriamin Forte;
- ama-nootropics - I-Cerebrolysate.
Kwezemidlalo, i-amino acid ithathwa ngendlela yezithako ze-BCAA eziqukethe i-isoleucine, i-leucine ne-valine.
Okuvame kakhulu yilezi:
- I-Optimum Nutrition BCAA 1000;
- I-BCAA 3: 1: 2 evela kuMusclePharm;
- I-Amino Mega Strong.
Intengo
Izindleko zomuthi i-Aminovena yesondlo sabazali zingama-ruble ayi-3000-5000 iphakethe ngalinye, eliqukethe izikhwama eziyi-10 ezingama-500 ml zesisombululo.
Intengo yethini elilodwa lesengezo semidlalo eliqukethe i-amino acid ebalulekile incike kumthamo nakumkhiqizi - kusuka kuma-ruble angama-300 kuye kwayi-3000.
